icon
body
VYNDAMAX is used to treat adults with wild-type or hereditary ATTR-CM to reduce death and hospitalization related to heart problems.
name
link
dismiss
false
image
Actor portrayal
mobile_image
Actor portrayal
eyebrow
headline

How VYNDAMAX works

content
buttons
disclaimer
headline

VYNDAMAX works by slowing the break down and build up of dangerous TTR deposits

content

ATTR-CM happens when a protein called transthyretin (TTR) breaks down and turns into amyloid. Amyloid can build up in the heart making it harder for the heart to pump effectively.

The TTR protein is mostly made in the liver and in smaller amounts in the outer lining of the brain and retina.

eyebrow
disclaimer
card_identifier
Illustration depicting VYNDAMAX (tafamidis) attaching to the ttr protein. See safety information.
Mobile_image
Illustration depicting VYNDAMAX (tafamidis) attaching to the ttr protein. See safety information.
Image_caption
heading

Attach

body
VYNDAMAX attaches to the TTR protein.
cta
card_identifier
Illustration depicting VYNDAMAX (tafamidis) stabilizing ttr after attaching to the protein. See safety info.
Mobile_image
Illustration depicting VYNDAMAX (tafamidis) stabilizing ttr after attaching to the protein. See safety info.
Image_caption
heading

Stabilize

body
VYNDAMAX stabilizes TTR, helping it stay together.
cta
card_identifier
A heart icon symbolizing VYNDAMAX (tafamidis) stabilizing ttr, slowing the breakdown and buildup of dangerous deposits and slowing the progression of ATTR-CM. See safety info.
Mobile_image
A heart icon symbolizing VYNDAMAX (tafamidis) stabilizing ttr, slowing the breakdown and buildup of dangerous deposits and slowing the progression of ATTR-CM. See safety info.
Image_caption
heading

Maintain

body
By stabilizing TTR, VYNDAMAX slows the breakdown and buildup of dangerous deposits, which can help to slow the progression of ATTR-CM.
cta
icon
headline

VYNDAMAX works by binding to the TTR protein, stabilizing it, and preventing it from breaking down

subheadline
content
disclaimer
buttons
eyebrow
headline
headline2

VYNDAMAX is a treatment with a Class 1* recommendation for ATTR-CM in guidelines from:

content
  • American College of Cardiology
  • American Heart Association
  • Heart Failure Society of America
content2
buttons
Cta_brightcove_account_id
Cta_brightcove_video_id
disclaimer
*Class 1 guidelines are given when there’s strong evidence or general agreement that a treatment is beneficial, useful, and effective. The above recommendation is from the 2022 guidelines.
icon
headline

Create a discussion guide to help you log your symptoms and talk to your doctor about ATTR-CM

subheadline

Questions to ask your doctor:

content
  • What causes ATTR-CM to develop?
  • Could my heart failure diagnosis and other symptoms be ATTR-CM?
  • If so, what are the next steps we should take to determine if I have ATTR-CM?
  • If I have ATTR-CM, could VYNDAMAX be right for me?
disclaimer
buttons
Get started
image
Mobile_image
eyebrow
headline

Hear from Stan, a real patient taking VYNDAMAX

subheadline
content
“Once I learned that VYNDAMAX can help to slow the progression of ATTR-CM, I was eager to begin the treatment journey.”
buttons
Hear from real patients
content2
disclaimer
Image_disclaimer
Brightcove_video_id
6372174251112
Brightcove_account_id
1852113022001
image
Vyndacares logo, a program that provides helpful information about ATTR-CM and VYNDAMAX (tafamidis). See safety info.
Mobile_image
Vyndacares logo, a program that provides helpful information about ATTR-CM and VYNDAMAX (tafamidis). See safety info.
eyebrow
headline

Get to the heart of what matters

subheadline
content
Stay informed with educational materials about ATTR-CM and VYNDAMAX.
buttons
Sign up
content2
disclaimer
Image_disclaimer
Brightcove_video_id
Brightcove_account_id
eyebrow
headline

Read about talking to your doctor

headline2
content
content2
buttons
Learn more
Cta_brightcove_account_id
Cta_brightcove_video_id
disclaimer